The Story Behind Nexafed Watch Video Touch the video to watch. Trust Nexafed Nexafed is the only meth-deterring pseudoephedrine (PSE) product with demonstrated bioequivalence to Sudafed® immediate-release tablets.1 Compare Recommend Nexafed You can make a difference in your community by stocking and recommending the modern decongestant of choice—Nexafed. Order Now Are you a healthcare professional? YESNO